Possible neuroprotective trait of Dysophylla auricularia methanol extract

Resumo

This study evaluated the inhibitory capacity of hydroxyl radical (^●OH), nitric oxide radical (NO^●), lipid peroxidation and acetylcholinesterase (AChE) activity of methanol extract of Dysophylla auricularia (MDA) whole plant. For this MDA at 50-200 µg/mL was tested by taking trolox (TRO: 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) as a standard. The TRO was used at 50 µg/mL. The results suggest that, MDA concentration-dependently exhibited strong antioxidant and anti-AChE activities. Significant (p <0.05) activity was observed in the MDA and TRO co-treatment group. D. auricularia may be one of the good sources of neuroprotective phytoconstituents.