Aplicabilidade da estereologia e microscopia de força atômica à pesquisa dermatológica veterinária (revisão de literatura)

Yago Gabriel da Silva Barbosa; Wanderson Gabriel Gomes de Melo Gomes Melo; Huanna Waleska Soares Rodrigues Soares Rodrigues; Napoleão Martins Argôlo Neto Martins Argolo Neto

doi:10.26694/jibi.v4i1.8596

Aplicabilidade da estereologia e microscopia de força atômica à pesquisa dermatológica veterinária (revisão de literatura)

Yago Gabriel da Silva Barbosa, Wanderson Gabriel Gomes de Melo Gomes Melo, Huanna Waleska Soares Rodrigues Soares Rodrigues, Napoleão Martins Argôlo Neto Martins Argolo Neto

Resumo

Em dermatologia veterinária, persiste a tradição morfológica de obtenção de dados essencialmente qualitativos. A estereologia e a microscopia de força atômica são técnicas que combinam estatística e microscopia avançada para obter informações quantitativas tridimensionais, como volume total, volume ultraestrutural, densidade volumétrica, número total de estruturas, dentre outras, a partir de imagens bidimensionais. Essas técnicas são cada vez mais relevantes para determinar a heterogeneidade morfológica comumente encontrada em amostras teciduais. A utilização concomitante dessas técnicas favorece a obtenção de dados matemáticos e físicos, os quais são mais fidedignos e de maior acurácia que dados morfológicos qualitativos, baseados em descrições morfométricas bidimensionais. Este trabalho consiste de uma pesquisa de natureza descritiva, na modalidade de pesquisa bibliográfica, a respeito do uso das técnicas de delineamento estereológico e microscopia de força atômica. Para tanto, foram selecionados artigos em inglês e português, de 2003 a 2019, a partir de bases de dados online (PUBMED, SCIELO). A estereologia e microscopias avançadas, como a microscopia de força atômica, são altamente relevantes pela capacidade de fornecimento de dados sofisticados e fidedignos na área de interesse, tornando úteis para práticas morfodescritivas veterinárias.

Palavras-chave

Estereologia; AFM; analise topográfica.

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DOI: https://doi.org/10.26694/jibi.v4i1.8596